Migraine Treatment and Drugs
A variety of drugs are actually specifically designed to help remedy migraines. In addition, some drugs very popular to treat various other conditions also might help relieve or avoid migraines. Medications used to help combat migraines fall under two broad different types:
* Pain-relieving medications. Also known as acute or abortive treatment, these types of drugs are consumed during migraine attacks and are created to stop symptoms which have already begun.
* Preventive medications. These types of drugs are consumed regularly, often on an everyday basis, to reduce the severity or rate of recurrence of migraines.
Choosing a technique to manage your migraines is determined by the frequency and severity of the headaches, the degree of disability your severe headaches cause, and your other health conditions.
Some medications aren’t recommended if you are pregnant or breast-feeding. Some aren’t for the use of children. Your doctor can help find the proper medication for you.
For best outcomes, take pain-relieving drugs whenever you experience signs or symptoms of the migraine. It may help in the event you rest or sleep inside a dark room soon after taking them:
Pain relievers. These medications, such as ibuprofen (Advil, Motrin, others) as well as acetaminophen (Tylenol, others) might help relieve mild migraine headaches. Drugs marketed especially for migraines, such as the mixture of acetaminophen, aspirin and caffeine (Excedrin Migraine), also may relieve moderate migraine discomfort but aren’t efficient alone for extreme migraines. If taken excessively or for a long time, these medications can result in ulcers, gastrointestinal bleeding as well as rebound headaches. The prescription pain reliever indomethacin might help thwart a migraine headache and can be found in suppository form, which may be helpful if you are nauseous.
Triptans. For many individuals with migraine attacks, triptans are the drug of preference. They are efficient in relieving the pain, nausea, and sensitivity to light and sound, which are associated with migraine headaches. Medications include sumatriptan (Imitrex), almotriptan (Axert), naratriptan (Amerge), zolmitriptan (Zomig), rizatriptan (Maxalt), frovatriptan (Frova) and also eletriptan (Relpax). Side effects associated with triptans include nausea or vomiting, dizziness and muscle tissue weakness. They aren’t recommended for individuals at risk regarding strokes and cardiovascular attacks. A single-tablet mixture of sumatriptan and naproxen sodium (Treximet) has proved more efficient in relieving migraine signs and symptoms than either medication by itself.
Ergot. Ergotamine and caffeine combination drugs (Migergot, Cafergot) are a lot less expensive, but also much less effective, than triptans. They seem most reliable in those whose pain lasts for over 48 hours. Dihydroergotamine (Deborah. H. E. 45, Migranal) is an ergot derivative that works more effectively and has fewer negative effects than ergotamine. It’s also available as being a nasal spray and also in injection form.
Anti-nausea medications. Because migraines in many cases are accompanied by nauseafeeling, with or devoid of vomiting, medication for nausea is suitable and is usually administered together with other medications. Frequently prescribed medicines are metoclopramide (Reglan) as well as prochlorperazine (Compro).
Opiates. Medications containing narcotics, particularly codeine, are sometimes helpful to treat migraine headache pain when individuals can’t take triptans as well as ergot. Narcotics are habit-forming and are also usually used only as being a last resort.
Dexamethasone. This corticosteroid can be utilized in conjunction with other medication to enhance pain relief. Because of the danger of steroid toxicity, dexamethasone should not be taken frequently.
You may become a candidate for preventive therapy should you have two or more debilitating attacks monthly, if pain-relieving medicines aren’t helping, or if your migraine symptoms include an extented aura or numbness in addition to weakness.
Preventive medications can slow up the frequency, severity and duration of migraines and may increase the potency of symptom-relieving medicines utilized during migraine episodes. Your doctor may suggest that you take preventive medications every day, or only whenever a predictable trigger, such as menstruation, is approaching.
In most situations, preventive medications tend not to eliminate headaches entirely, and some cause serious negative effects. If you have experienced good results through preventive medicine and have been migraine-free for half a year to 12 months, your doctor might recommend tapering off the medication to see if the migraines return devoid of it.
For best outcomes, take these medications as your personal doctor recommends:
Cardiovascular drugs. Beta blockers – widely used to treat excessive blood pressure as well as coronary artery condition – can slow down the frequency and intensity of migraines. The beta blocker propranolol (Inderal La, Innopran XL, others) has proved effective for preventing migraines. Calcium channel blockers, another class connected with cardiovascular drugs, especially verapamil (Calan, Verelan, others), also may possibly be helpful in avoiding migraines and minimizing symptoms from aura. In addition, the antihypertensive treatment lisinopril (Zestril) continues to be useful in reducing the length and severity of migraines. Researchers don’t understand precisely why these cardiovascular medications prevent migraine problems. Side effects range from dizziness, drowsiness or lightheadedness.
Antidepressants. Certain antidepressants are efficient at helping to prevent some kinds of headaches, including migraines. Tricyclic antidepressants, such as amitriptyline, nortriptyline (Pamelor) and also protriptyline (Vivactil) in many cases are prescribed for migraine avoidance. Tricyclic antidepressants may reduce migraine headaches by affecting the amount of serotonin and some other brain chemicals, though amitriptyline is alone proved to be efficient for migraine headaches. You don’t need to have depression to make use of these drugs. Other classes of antidepressants called selective serotonin reuptake inhibitors (SSRIs) and also serotonin-norepinephrine reuptake inhibitors (SNRIs) have not been proved as effective for migraine headache prevention. However, preliminary research shows that one SNRI, venlafaxine (Effexor, Venlafaxine HCL), may be useful in preventing migraine headaches.
Anti-seizure medications. Some anti-seizure medications, such as valproate (Depacon), topiramate (Topamax) and also gabapentin (Neurontin), seem to slow down the frequency of migraine headaches. Lamotrigine (Lamictal) might be helpful for those who have migraines with aura. In high dosages, however, these anti-seizure drugs could cause side effects, such as nausea and vomiting, hair loss, diarrhea, cramps, and dizziness.
Cyproheptadine. This antihistamine particularly affects serotonin activity. Doctors sometimes allow it to children like a preventive measure.
Botulinum toxin type A (Botox). The FDA offers approved botulinum toxin type A for treatment of chronic migraine headaches in adults. During this process, injections are made in muscles of your forehead and throat. When this works well, the treatment typically must be repeated every 12 weeks.